의과대학 - 의과대학

  • 교수 해부학, 신경과학, 줄기세포 재생의학
  • 이경훈

관심분야

Degenerative diseases of the nervous system
Regeneration of the nervous system
Stem cell therapy of the brain & spinal cord injury

학력

  • (Ph.D.) Seoul National University, College of Medicine
  • (M.D.) Seoul National University, College of Medicine

약력/경력

  • 1995.3-1997.2: Assistant professor, Dankook university College of medicine
  • 1998.3-현재: Assistant professor, Associate professor, Professor
  • Sungkyunkwan university School of medicine
  • 2001.3-2003.2: Visiting professor, Ohio State University College of Medicine, U.S.A.

학술지 논문

  • (2023)  The nail matrix onychodermis – the curious reason behind the color of the lunula.  INTERNATIONAL JOURNAL OF DERMATOLOGY.  1,  1
  • (2022)  The effects of early exercise in traumatic brain-injured rats with changes in motor ability, brain tissue, and biomarkers.  BMB REPORTS.  55,  10
  • (2022)  Combination stem cell therapy using dental pulp stem cells and human umbilical vein endothelial cells for critical hindlimb ischemia br.  BMB REPORTS.  55,  7
  • (2022)  Significant Therapeutic Effects of Adult Human Neural Stem Cells for Spinal Cord Injury Are Mediated by Monocyte Chemoattractant Protein-1 (MCP-1).  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.  23,  8
  • (2021)  Effects of Long-Term In Vitro Expansion on Genetic Stability and Tumor Formation Capacity of Stem Cells.  STEM CELL REVIEWS AND REPORTS.  18,  1
  • (2021)  Single-cell RNA sequencing of human nail unit defines RSPO4 onychofibroblasts and SPINK6 nail epithelium.  COMMUNICATIONS BIOLOGY.  4,  1
  • (2021)  Optimal Preclinical Conditions for Using Adult Human Multipotent Neural Cells in the Treatment of Spinal Cord Injury.  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.  22,  5
  • (2019)  Roles of ErbB3-binding protein 1 (EBP1) in embryonic development and gene-silencing control.  PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA.  116,  49
  • (2018)  The Brain Donation Program in South Korea.  YONSEI MEDICAL JOURNAL.  59,  10
  • (2018)  Significant therapeutic effects of adult human multipotent neural cells on spinal cord injury.  SOFT MATTER.  14,  5
  • (2017)  CD13 is a marker for onychofibroblasts within nail matrix onychodermis: Comparison of its expression patterns in the nail unit and in the hair follicle.  JOURNAL OF CUTANEOUS PATHOLOGY.  44,  11
  • (2017)  Angiogenic Capacity of Dental Pulp Stem Cell Regulated by SDF-1α-CXCR4 Axis.  STEM CELLS INTERNATIONAL.  1,  1
  • (2017)  The Concept of Onychodermis (Specialized Nail Mesenchyme) Is Applicable in Normal Adult Nail Unit.  ANNALS OF DERMATOLOGY.  29,  2
  • (2017)  Therapeutic effects of hyaluronidase on acquired lymphedema using a newly developed mouse limb model.  EXPERIMENTAL BIOLOGY AND MEDICINE.  242,  6
  • (2016)  Akt1-Inhibitor of DNA binding 2 is essential for growth cone formation and axon growth and promotes central nervous system axon regeneration.  ELIFE.  5, 
  • (2016)  Multipotent neurogenic fate of mesenchymal stem cell is determined by Cdk4-mediated hypophosphorylation of Smad-STAT3.  CELL CYCLE.  15,  13
  • (2016)  Avoiding student infection during a Middle East respiratory syndrome (MERS) outbreak: a single medical school experience.  한국의학교육학회지.  28,  2
  • (2016)  Akt attenuates apoptotic death through phosphorylation of H2A under hydrogen peroxide-induced oxidative stress in PC12 cells and hippocampal neurons.  SCIENTIFIC REPORTS.  6,  1
  • (2015)  P42 Ebp1 functions as a tumor suppressor in non-small cell lung cancer.  BMB REPORTS.  48,  3
  • (2014)  P42 Ebp1 regulates the proteasomal degradation of the p85 regulatory subunit of PI3K by recruiting a chaperone-E3 ligase complex HSP70/CHIP.  CELL DEATH & DISEASE.  5, 

단행본

  • (2021)  사람발생학.  범문에듀케이션.  공동
  • (2005)  국소해부학.  고려의학.  공동
  • (2004)  소보타 원색인체해부학.  신흥메드사이언스.  공동
  • (2004)  발생학 Board review series.  신흥메드사이언스.  공동
  • (2004)  신경해부학 Board review series.  신흥메드사이언스.  공동
  • (2003)  스넬 임상신경해부학.  신흥메드사이언스.  공동
  • (2003)  인체조직학.  정문각.  공동
  • (2002)  조직학 사진문제집.  범문사 (Churchill Livingstone).  공동
  • (2002)  사람발생학 (Langmans Medical Embryology), 8판.  범문사 (Lippincott Williams & Wilkins Publishers).  공동
  • (2002)  국소해부학.  고려의학.  공동
  • (1999)  해부학.  고려의학.  공동
  • (1999)  생생 사진해부학(Photographic atlas of practical anatomy).  현문사.  단독

특허/프로그램

  • 후천성 림프부종 동물모델 및 이의 제조방법.  10-2012-0040020.  20141223.  대한민국

수상/공훈

  • Member: Society for neuroscience (U.S.A)
  • Member: The korean society of medical education
  • Member: The korean society for brain and neural science
  • Member: Korean association of anatomists

학술회의논문

  • (2019)  Treatment and Therapeutic Interventions for Spinal Cord Injury.  2019 society for neuroscience conference.  미국
  • (2019)  Enhanced Therapeutic Effects by Combining Dental Pulp Stem Cells and Human Umbilical Vein Endothelial Cells for Critical Hindlimb Ischemia.  2019 ISSCR annual meeting.  미국
  • (2014)  AKT regulates Id2 for axonal regeneration in CNS.  2014 annual meeting of society for neuroscience.  미국
  • (2014)  The role of phosphorylated p48 Ebp1 in glioblastoma.  2014 annual meeting of society for neuroscience.  미국
  • (2014)  Tumor suppressor p42 Ebp1 controls p85 regulatory subunit of PI3K stability in GBM.  2014 annual meeting of society for neuroscience.  미국
  • (2014)  Akt mediated phosphorylation of Histone H2A contributes the functional regulation of H2A.  2014 annual meeting of society for neuroscience.  미국
  • (2014)  Id2 is a key player for CNS axonal regeneration.  2014 KSBMB annual meeting.  대한민국
  • (2013)  Akt mediated phosphorylation of Histone 2A interrupts acetylation of Histone H2A.  2013 KSBMB annual meeting.  대한민국
  • (2013)  B23 regulates neuronal polarity by transport of PIP3.  International Conference of the Korean Society for Molecular and Cellular Biology.  대한민국
  • (2013)  SIAH1 modulates axon generation and specification through ubiquitination of AKT.  2013 KSBMB annual meeting.  대한민국
  • (2013)  p42Ebp1 regulates tumor growth by inhibiting PI3K activity.  International Conference of the Korean Society for Molecular and Cellular Biology.  대한민국
  • (2012)  S-nitrosylated B23/nucleophosmin (NPM) regulates Siah1, preventing Siah1/GAPDH mediatedneuronal cell death.  Annual meeting of the American society for cell biology.  미국
  • (2012)  Tumor suppressor p42 Ebp1 controls p85 regulation subunit of PI3K stability.  2012 KSMCB annual meeting.  대한민국
  • (2012)  Nuclear Akt promotes neurite outgrowth in the early stage of neuritogenesis.  2012 Annual meeting of Korean Society for Biochemistry and Molecular Biology.  대한민국
  • (2011)  Tumor suppressor p42 Ebp1 control PI3K stability in human glioma.  2011 Annual meeting of Society for Neuroscience.  미국
  • (2011)  Akt phosphoryaltion couples Id2 stability and neurite outgrowth.  2011 Annual meeting of Society for Neuroscience.  미국
  • (2011)  The short isoform of ErbB3 binding protein p42 regulates PI3K activity through direct binding to regulatory subunit p85 of PI3K.  2011 KSBMB annual meeting.  대한민국
  • (2010)  Phosphorylation of p48 regulates tumorigenesis of human malignant glioma.  40th Annual Meeting The Society for Neuroscience.  미국
  • (2010)  The Role of NPM/B23 in Establishment of Neuronal Polarity.  40th Annual Meeting The Society for Neuroscience.  미국
  • (2009)  Regulation of neuronal differentiation by Akt-dependent Id2 phosphorylation.  2009 Annual meeting of society for neuroscience.  미국